Tuxford is bypassed by the A1 trunk road and the A57 which links Tuxford to a number of major towns and cities, with London just over two hours away.
The Great North Road runs through the village (now B1164), though the majority of traffic now uses the modern A1 trunk road, which splits the village in two.
The town is also served by a number of buses operated by Stagecoach in Bassetlaw, Stagecoach in Lincolnshire, TM Travel as well as smaller local bus operators, to destinations including Worksop, Newark, Nottingham and Doncaster.
Despite its small size, Tuxford had three railway stations but all are now closed.
The nearest railway stations are in Retford and Lincoln.
Retford is served by two railway lines, the East Coast Main Line which runs between London and Scotland, with trains taking from 1hr 20 minutes to London Kings Cross, and the Sheffield to Lincoln Line which has links to Sheffield, Lincoln, Gainsborough, Worksop, Grimsby and Cleethorpes. These two lines meet at Retford railway station which acts as an important interchange in the British rail network.
Lincoln Central has five platforms and a steady flow of trains and passengers. Trains run to various destinations including Newark-on-Trent, Grimsby and Peterborough. In May 2010, East Coast began a new direct train service to London, calling at Newark, Peterborough and Stevenage. One service in each direction operates daily, but there is only a northbound journey on Sundays.
Retford is connected to the UK Inland Waterways network by the Chesterfield Canal. Indeed, up to Retford the canal was built to be accessible by broad-beam boats rather than the more usual narrowboats, Retford Town Lock being the first narrow lock on the canal from its junction with the River Trent at West Stockwith. However, narrow sections now prevent such craft reaching Retford. The canal starts at Chesterfield in Derbyshire. Based in Retford on the lower side of the Town Lock is a boat club called Retford Mariners Boat Club (R.M.B.C), it was formed in November 1978 by a group of canal enthusiasts.
Robin Hood Airport (formerly RAF Finningley) is nearby on the A638 towards Doncaster. A regular bus service is available from Retford bus station to the airport, which offers regular flights to other European countries. Due to its military past, Robin Hood airport has a long 2,580 metres (8,460 ft) runway, and so is capable of landing wide body jets such as Boeing 747s, and has plans of extending its destinations to include the USA. The popular discount airline easyjet, commenced flying to many European destinations in March 2010, but withdrew by the end of the year citing commercial factors as a reason. The Hungarian airline WizzAir continues to serve several Eastern-European cities, and Thomson Holidays regularly runs charter services from there as part of their package holiday business.
Retford (Gamston) Airport is a private airport located a few miles south of Retford in the village of Gamston, operated by Gamston Aviation Ltd.